pysam
Genomic file toolkit for NGS data processing. Read/write SAM/BAM/CRAM alignments, VCF/BCF variants, and FASTA/FASTQ sequences using Pysam with a Pythonic interface to htslib.
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231 skills found
Genomic file toolkit for NGS data processing. Read/write SAM/BAM/CRAM alignments, VCF/BCF variants, and FASTA/FASTQ sequences using Pysam with a Pythonic interface to htslib.
Build modular FastAPI applications using Clean Architecture, including domain-driven design, dependency injection, repository patterns, and testing strategies for scalable Python backend services.
Comprehensive AI-generated text detection framework. Features multi-layer analysis of vocabulary, structural patterns, model-specific fingerprints, and technical metadata artifacts to identify AI authorship.
Parses and processes SARIF files from static analysis tools. Enables aggregation, deduplication, filtering, and CI/CD integration of scan results.
Automated GitHub issue analysis, triage, and resolution planning tool integrated with Specification Driven Development (SDD) workflows.
Automates the documentation of solved technical issues using YAML frontmatter, categorized directories, and institutional knowledge indexing for JUCE plugin development.
Full-stack application orchestrator that analyzes natural language requests to determine tech stacks, scaffold projects, and coordinate specialized development agents.
Implementation patterns for MERIDIAN autonomous AI agents using Claude API, including BaseAgent lifecycle, structured tool use, token budget enforcement, and cron scheduling.
Master KPI dashboard design with proven metrics frameworks, SMART goals, and hierarchy patterns to drive business performance from executive insights to operational monitoring.
Generate professional markdown newsletters from localized events stored in SQLite. Automates event aggregation, curation, and formatting for community or niche media newsletters.
Architect and optimize production-grade RAG systems. Master embedding models, vector databases, chunking strategies, and retrieval pipelines for high-accuracy LLM applications.
Translate research papers (markdown) while preserving LaTeX formulas, code blocks, and images, with support for batch processing, retries, and portable bundles.